Genuine diamond powder visually smooths out fine lines, wrinkles and pores, thereby counteracting the external signs of premature skin ageing. The fine, shimmering particles also give the skin a soft, alluring glow (instant glow effect).

Ectoin acts as a natural DNA and cell protective factor against UV-induced skin damage, supports the skin’s immune system and ensures the skin can effectively defend itself against stress. Ectoin has been identified as the substance that protects organisms in the desert from intense sunlight, high temperatures and extreme dryness. Ectoin is used as an active ingredient in skincare and sun protection products. It stabilises the natural structure of biopolymers such as proteins, nucleic acids and biomembranes. It has been proven to protect against skin damage caused by UVA and UVB radiation. What makes it special is that ectoin does not act as a UV filter, but rather as a preventative cellular protector against sun allergies, UV-induced skin ageing and photodermatoses. Ectoin prevents damage to the epidermis and the deeper layers of the skin. When combined with UV filters, it provides highly effective skin protection. Furthermore, ectoin protects the skin’s own immune system.

The common ash (Fraxinus excelsior) is a large tree commonly found in European forests. Its bark contains two glucosides which actively reduce the permeability of blood capillaries. This activity, known as vitamin P activity (P for permeability), has a vein-strengthening and vasoprotective effect. These two glucosides also have an antioxidant effect, which not only improves the protection of the blood capillaries but also prevents the breakdown of haemoglobin into coloured compounds, thereby preventing the appearance of dark circles and shadows under the eyes.

The extract from fingerweed or green algae (Codium fragile) stimulates cell metabolism and cell growth, and intensively regenerates the skin. The algae extract also has an antioxidant effect against free radicals, which are partly responsible for skin ageing.

Multi-active AntiOx or HDBM (hydroxy-dimethoxybenzyl malonate) effectively and continuously reduces free radicals over a 24-hour period, provides controlled and long-lasting protection against oxidative stress, and thus specifically prevents premature skin ageing.

Bio-chromones are newly developed plant-based active ingredients that deeply reactivate the skin’s renewal process, boost collagen production and inhibit its breakdown. This reduces fine lines and provides long-lasting firming of the skin tissue.

Ceramides are fatty substances that form part of the epidermal lipids. As key building blocks of the skin, ceramides play a vital role in enabling the skin to fulfil its protective function. In the Lubex anti-age® active treatments, ceramides 1, 3 and 6 help to maintain healthy skin, ensuring that it can fulfil its protective role as a barrier against external substances and does not become dehydrated.

Thanks to the regenerative properties of lutein, Goldella helps to control inflammation and protect cell vitality, thereby regenerating all layers of the skin damaged by oxidative stress. Goldella improves skin quality and reduces fine lines.

Coenzyme Q10 boosts collagen production, reactivates the skin’s renewal process deep within the skin, firms the skin tissue and reduces fine lines. Coenzyme Q10 is included in various Lubex anti-age® active treatments in a highly pure liposomal form, enabling the active ingredient to exert its full effectiveness within the skin.

Colorless carotenoids are plant-based active ingredients extracted from tomatoes, which have powerful antioxidant properties. They combat free radicals to protect the skin from the ageing effects of UV light and environmental pollution.

Blocks the formation of free radicals caused by infrared and blue light. Protects mitochondrial DNA. Prevents light-induced skin ageing. Prevents the loss of skin density caused by sun exposure.

Hyaluronic acid is a key component of the connective tissue found between skin cells, where it fills and supports the tissue. Thanks to its ability to bind large amounts of water, hyaluronic acid plays an essential role in maintaining the skin’s moisture levels. The hyaluronic acid active ingredients therefore also help to keep the epidermis firm. There are few, if any, allergies or side effects associated with hyaluronic acid ingredients, as they are physiologically compatible and recognised by the body. Hyaluronic acid ingredients are available in various molecular sizes:

Restores the skin barrier by stimulating epidermal lipid synthesis and accelerating its regeneration. Helps the skin to defend itself by strengthening its ability to recognise pathogens. Restores balance to the skin’s ecosystem and reduces dryness.

Only those active ingredients that meet the strict requirements for therapeutic efficacy in terms of active ingredient content and purity are designated as high-purity active ingredients. In the manufacture of Lubex anti-age®, Permamed attaches great importance to the use of high-purity active ingredients. Permamed specialises in developing and manufacturing formulations in accordance with the latest scientific criteria, ensuring that even highly sensitive skin can tolerate Lubex anti-age® products without any problems.

Stimulates the skin’s own production of hyaluronic acid and reduces fine lines.

Highly concentrated soya isoflavone liposomes significantly increase skin thickness – which decreases with ageing – and rebuild the dermis and epidermis from within. Isoflavones have been used for several years to treat menopausal symptoms in women. This active ingredient can also be used in skincare. Our active ingredient manufacturers mostly use isoflavones derived from red clover, soya beans, iris and wild yam. These plant-based oestrogens have a wide range of functions. Above all, they can counteract the decline in collagen and elastin production in the skin.

Jojoba is an evergreen shrub that is native mainly to the semi-deserts and deserts of Mexico, California and Arizona. Its seeds contain a liquid wax (the term ‘oil’ is not technically correct, but has become established in common usage), which is used for cosmetic purposes. It prevents the skin from drying out.

Kahai oil is extracted from the Kahai nut, which is sustainably sourced from the Amazon region. Kahai oil significantly reduces wrinkles and firms the skin. Its anti-ageing effect has been proven by a scientific study. Kahai oil is quickly absorbed by the skin, leaving no greasy film on the skin’s surface. The oil is rich in vitamins E and F, and retinol.

The shoots of garden cress (Lepidium sativum) contain the highest concentration of phytochemicals – the compounds in plants known for their health-promoting properties. One of these phytochemicals, sulforaphane, reduces melanin production and thus has a lightening effect on pigmentation and age spots. When combined with soya isoflavones, this effect is synergistically enhanced and pigmentation spots are specifically reduced without lightening the surrounding skin: this results in a more even complexion.

Microalgae extract instantly and noticeably firms the skin, makes it more elastic, stimulates collagen production and thus also firms the skin in the long term.

Microcapsules are tiny enclosures for particularly sensitive active ingredients. They are used primarily in the medical sector. In Lubex anti-age®, the sensitive active ingredients are encapsulated in special, patented microcapsules (cyclodextrin). This ensures that the high-purity active ingredients are optimally protected against the harmful effects of light and oxygen, even after they have been applied to the skin! They can therefore unfold their full effectiveness and remain active for hours.

Niacinamide, also known as vitamin B3, is a powerful cell-communication active ingredient that offers several benefits for ageing skin: it improves the skin’s elasticity and significantly enhances its barrier function. Niacinamide has been shown to increase the levels of ceramides and free fatty acids in the skin, prevent water loss from the skin and stimulate microcirculation in the dermis. It is also effective at treating and evening out an uneven complexion, as well as revitalising the skin’s texture. It is an excellent active ingredient for combating wrinkles and skin imperfections.

It is a high-quality elixir derived from the prickly pear (Opuntia ficus-indica), which blocks the release of stress markers from the sensory nerve cells in the skin, thereby soothing and calming irritated skin. It has excellent moisturising properties.

PCA (pyrrolidone carboxylic acid) is a natural moisturising factor in the skin that intensely hydrates the epidermis and protects it from drying out.

Peptides are important signalling molecules and building blocks of the skin. They play a key role in wound-healing research, as the formation of new skin cells is crucial to the success of treatment.

• Acetyl Tetrapeptide Improves blood circulation in the skin under the eyes. Puffiness is reduced and dark circles are lightened. The active ingredient also strengthens the skin barrier and promotes collagen production, resulting in firmer and smoother skin overall.
• Dipeptide complex: Smooths expression lines by relaxing the facial muscles. Thanks to the so-called ‘age-killing’ effect, forehead lines, laugh lines and expression lines are visibly reduced.
• Tripeptides accelerate the shedding of dead surface skin cells, leaving the skin smoother, finer and more radiant.• Tetrapeptides help to reduce puffiness under the eyes and minimise dark circles.
• Hexapeptides work by inhibiting the release of neurotransmitters, which reduces facial muscle contractions – similar to Botox – thereby minimising expression lines.
• Pentapeptides reduce muscle contraction and prevent the formation of wrinkles.

Instantly mattifies the skin and refines the pores.

See vitamin C glucosides.

Provitamin E is vitamin E in a stabilised form. The human body can store vitamin E, meaning that a single dose can be effective for an extended period. Provitamin E acts as an antioxidant against free radicals, helping to repair and regenerate skin that has been damaged by UV rays.

Resveratrol, a sirtuin (SIRT 1) activator, protects DNA and increases the longevity of skin cells. Thanks to innovative liposomal microencapsulation, this bioactive ingredient is delivered directly to the cells of the epidermis, improving skin vitality and slowing down the skin ageing process.

Retinol (vitamin A) boosts collagen production, reactivates the skin’s renewal process deep within the skin, firms the skin tissue and reduces fine lines. It is present in a highly pure, microencapsulated form, allowing the active ingredient to exert its full effect on the skin and remain active for hours.

Retinyl palmitate boosts collagen production, deeply activates the skin’s renewal process and repairs skin damage: maximum anti-wrinkle effectiveness with excellent tolerability

The quality of the raw materials used in all Lubex products meets the highest quality standards. Where fragrances are used, they comply with the IFRA standard, the strict standard set by the International Fragrance Association. All these fragrances are hypoallergenic, meaning they do not contain any of the 26 allergenic fragrance ingredients that can cause allergies and which must therefore be declared on the product packaging. It goes without saying that all Permamed products are free from musk and formaldehyde. Furthermore, all Lubex anti-age® products generally do not contain preservatives (such as parabens), as these are often allergenic and can irritate the skin.

The term ‘stem cells’ generally refers to body cells that can differentiate into various cell types or tissues. Plants also possess stem cells. Researchers have discovered that plant stem cells contain epigenetic factors similar to those found in human stem cells. When used skilfully, these can have a positive effect on the functionality and vitality of skin stem cells. Comprehensive studies have shown that Malus domestica stem cells promote the vitality of skin stem cells and effectively accelerate cell renewal.

Leaves the skin feeling comfortable and supports skin regeneration. In the human body, squalane is found in small quantities in the skin’s lipid layers, where it protects the skin barrier against moisture loss.

Reduces blemishes and firms the skin.

Vitamin C glucosides (provitamin C) are a stabilised form of vitamin C. Vitamin C glucosides act as antioxidants against free radicals, reduce and prevent pigmentation spots, repair skin damaged by UV rays and thus actively combat skin ageing.